国家自然科学基金面上项目(立体选择性酶催化-离心逆流萃取耦合连续拆分对映体过程研究,编号21676077),起止时间:2017-2020;
国家重点基础研究发展计划(973计划)项目(复杂手性萃取化工过程优化与节能研究,编号2014CB260407) 起止时间:2015-2016;
国家自然科学基金面上项目(基于反应萃取的高速逆流色谱手性分离新技术,编号21376071),起止时间:2014-2017;
国家自然科学基金面上项目(手性BINAP金属配合物反应萃取分离α-氨基酸对映体研究,编号21171054),起止时间:2012-2015;
国家自然科学基金面上项目(包合反应萃取分离芳香酸对映体及动力学研究,编号20976041),起止时间:2010-2012;
国家自然科学基金面上项目(双相(W/O)识别手性萃取分离对映体的研究,编号20776038),起止时间:2008-2010;
国家自然科学基金面上项目(分子识别真空纤维膜分步萃取分离天然酯型儿茶素的研究,编号20576029),起止时间:2006-2008;
湖南省自然科学***基金项目(反应萃取分离疏水性药物对映体热力学及动力学研究,编号10JJ1004),起止时间:2010-2012
人才计划:
教育部新世纪优秀人才支持计划(编号NCET-08-0678),起止时间:2009-2011
[1] Kewen Tang*, Hui Zhang, Yongbing Liu. Experimental and simulation on enantioselective extraction incentrifugal contactor separators. AIChE J., 2013; 59(7): 2594–2602.
[2] Kewen Tang*, Panliang Zhang, Chunyue Pan, Hongjian Li. Equilibrium studies on enantioselective extraction of oxybutynin enantiomers by hydrophilic β-cyclodextrin derivatives. AIChE J., 2011;57(11):3027–3036. (Top Cited AIChE Journal paper)
[3] Kewen Tang*, Jianmin Yi, Yongbing Liu, Xinyu Jiang, Yang Pan. Enantioselective separation of R,S-phenylsuccinic acid by biphasic recognition chiral extraction. Chem. Eng. Sci., 2009;64:4081–4088. (The most cited author)
[4] Kewen Tang*, Jiabing Miao, Tao Zhou, Yongbing Liu, Litao Song. Reaction kinetics in reactive extraction for chiral separation of α-cyclohexyl-mandelic acid enantiomers with hydroxypropyl-β-cyclodextrin. Chem. Eng. Sci., 2011;66(3): 397–404.
[5] Kewen Tang*, Hui Zhang, Panliang Zhang. Continuous separation of α-cyclohexyl-mandelic acid enantiomers byenantioselective liquid–liquid extraction in centrifugal contactor separators: experiments and modeling. Ind. Eng.Chem. Res., 2013; 52 (10): 3893–3902.
[6] Kewen Tang*, Jian Cai, Panliang Zhang. Equilibrium and kinetics of reactive extraction of ibuprofen enantiomers from organic solution by HP-β-CD. Ind. Eng. Chem. Res., 2012;51:964–971.
[7] Kewen Tang*, Guohui Wu, Panliang Zhang, Jiajia Liu, Congshan Zhou. Experimental and model study onenantioselective extraction of phenylglycine enantiomers with BINAP-Metal complexes. Ind. Eng. Chem. Res.,2012; 51(46): 15233–15241.
[8] Kewen Tang*, Xiaofeng Feng, Panliang Zhang, Shuangfeng Yin, Congshan Zhou, Changan Yang, Experimental and Model Study on Multistage Enantioselective Liquid-Liquid Extraction of Ketoconazole Enantiomers in CentrifugalContactor Separators. Ind. Eng. Chem. Res. 2015; 54: 8762-8771.
[9] Kewen Tang*, Litao Song, Yongbing Liu, Yang Pan, Xinyu Jiang. Separation of flurbiprofen enantiomers by biphasic recognition chiral extraction. Chem. Eng. J., 2010;158(1):411-417.
[10] Kewen Tang*, Litao Song, Yongbing Liu, Jiabing Miao. Enantioselective partitioning of 2-phenylpropionic acid enantiomers in a biphasic recognition chiral extraction system. Chem. Eng. J., 2012;180:293–298.
[11] Kewen Tang*, Jian Cai, Changan Yang, Yuejin Liu, Panliang Zhang, Yongbing Liu. Kinetics study on reactive extraction for chiral separation of oxybutynin enantiomers. Sep. Purif. Technol., 2012;92:30–35.
[12] Kewen Tang*, Yuanyuan Chen, Jiajia Liu. Resolution of Zopiclone enantiomers by biphasic recognition chiral extraction. Sep. Purif. Technol., 2008;62:681–686.
[13] Kewen Tang*, Jianmin Yi, Kelong Huang, Guoli Zhang. Biphasic recognition chiral extraction: a novel method for seperation of mandelic acid enantiomers. Chirality, 2009;21: 390–395.
[14] Kewen Tang, Xiaofeng Feng, Panliang Zhang*, Weifeng Xu*, Experimental and Model Study on Separation of α-Cyclopentylmandelic Acid Enantiomers by Liquid–Liquid Extraction, J. Chem. Eng. Data, 2016, 61(9): 3090–3097.
[15] Kewen Tang*, Tao Fu, Panliang Zhang. Equilibrium studies on enantioselective liquid–liquid extraction ofphenylalanine enantiomers using BINAP–Metal complexes. J. Chem. Eng. Data, 2012;57(12):3628–3635.
[16] Kewen Tang*, Panliang Zhang. Experimental and modeling studies on the enantioselective extraction of hydrophobicpranoprofen enantiomers with hydrophilic β-cyclodextrin as selectors. J. Chem. Eng. Data, 2011; 56 (10): 3902–3909.
[17] Kewen Tang*, Tao Fu, Panliang Zhang. Equilibriumstudies on enantioselective liquid–liquid extraction of homophenylalanine enantiomers with metal-BINAP complexes. Process Biochem., 2012;47(12):2275–2283.
[18] Kewen Tang*, Panliang Zhang, Hongjian Li. Experimental and model study on the multiple chemical equilibrium for reactive extraction of ibuprofen enantiomers with HP-β-CD as hydrophilic selector. Process Biochem., 2011;46:1817–1824.
[19] Kewen Tang*, Ping Wen, Panliang Zhang, Yan Huang. Studies on multistage enantioselective liquid–liquid extraction of amino-(4-nitro-phenyl)-acetic acid enantiomers using CuPF6{(S)-BINAP}: Experiments and modeling. Sep. Purif. Technol., 2014, 134: 100-109.
[20] Panliang Zhang, Hui Zhang, Kewen Tang*, Jianmin Yi, Yan Huang. Influence of pH on enantioselective extraction of aromatic acid enantiomers in centrifugal contactor separators: experiments and simulation. Sep. Purif. Technol., 2015, 141: 68-75.
[21] Panliang Zhang, Genlin Sun, Kewen Tang*, Congshan Zhou, Changan Yang, Weijun Yang. Separation of amlodipine besilate enantiomers by biphasic recognition recycling high-speed counter-current chromatography. Sep. Purif. Technol., 2015, 146: 276–283.
[22] Kewen Tang*, Hongjian Li, Panliang Zhang. Kinetic study on biphasic recognition chiral extraction for separation of α-cyclohexylmandelic acid enantiomers. J. Chem. Technol. Biotechnol., 2012;87(7):976–982.
[23] Panliang Zhang, Guilin Dai, Weifeng Xu, Kewen Tang*. Kinetics of reactive extraction of equol enantiomers from organic phase by hydroxypropyl-β-cyclodextrin, Sep. Purifi. Technol., 2016, 170: 314-320.
[24] Kewen Tang*, Yaqiong Wang, Panliang Zhang, Yan Huang*, Jie Hua, Optimization study on continuous separation of equol enantiomers using enantioselective liquid–liquid extraction in centrifugal contactor separators. Process Biochem. 2016, 51(1): 113–123.
[25] Panliang Zhang, Na Xie, Kewen Tang*, Xiaoming Chen, Weifeng Xu*, Modeling and optimization of two phase system for recycling high-speed counter-current chromatographic separation of ketoconazole enantiomers. Sep. Purifi. Technol. 2016, 164: 41–48.